Recent technology advances, especially in computing and mobile phone technology, offer new possibilities for both the promotion of positive health behaviours and the management of rehabilitation that were unimaginable even a decade ago.  Mobile phone apps provide a vehicle for monitoring the health and health behaviour of individuals, groups and, potentially, populations and for administering health interventions on a mass scale to a large, geographically diverse, and frequently remote target groups.  Computer-based, interactive programs make possible innovative therapeutic and rehabilitative interventions while enhancements in mobile coverage, network connectivity and bandwidth provide a basis for tele-health interventions, and specialist diagnostic service provision, to remote communities that were previously unattainable.  Research at UQ seeks to both develop new applications and systematically examine their efficacy and effectiveness in changing health behaviours, improving health care delivery, and positively impacting upon health outcomes for disadvantaged sectors of the population.